Marie Sissler Selected Research

Aspartate-tRNA Ligase

12/2015	Neurodegenerative disease-associated mutants of a human mitochondrial aminoacyl-tRNA synthetase present individual molecular signatures.
3/2013	Pathogenic mutations causing LBSL affect mitochondrial aspartyl-tRNA synthetase in diverse ways.
2/2011	A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria.

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Marie Sissler Research Topics

Disease

4	Leukoencephalopathies 12/2015 - 04/2007
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 12/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2019
1	Pontocerebellar Hypoplasia Type 6 01/2018
1	Neurodevelopmental Disorders 01/2018
1	Nonsyndromic Deafness 03/2015
1	Leigh Disease (Leigh's Disease) 03/2015
1	Hearing Loss (Hearing Impairment) 03/2015
1	Muscular Diseases (Myopathy) 08/2009

Drug/Important Bio-Agent (IBA)

3	EnzymesIBA 01/2019 - 02/2011
3	Aspartate-tRNA LigaseIBA 12/2015 - 02/2011
2	Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Lactate ElevationIBA 01/2018 - 04/2007
2	Lactic Acid (Lactate)FDA LinkGeneric 03/2013 - 04/2007
1	Ligases (Synthetase)IBA 12/2015
1	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 12/2015
1	Transfer RNA (tRNA)IBA 12/2015
1	asparaginyl-tRNA synthetaseIBA 03/2015
1	Complement System Proteins (Complement)IBA 03/2015
1	Proteins (Proteins, Gene)FDA Link 03/2015
1	Asn Transfer RNAIBA 03/2015
1	Mutant Proteins (Protein, Mutant)IBA 03/2015
1	Asp Transfer RNAIBA 08/2009
1	NucleotidesIBA 08/2009